Chronic mild stress-induced protein dysregulations correlated with susceptibility and resiliency to depression or anxiety revealed by quantitative proteomics of the rat prefrontal cortex

Abstract Chronic stress is a significant risk factor for depression as well as anxiety disorders. Yet, the stress-induced specific and common molecular dysregulations of these disorders have not been fully understood. Previously, we constructed a chronic mild stress (CMS) rat model to separate and o...

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Bibliographic Details
Main Authors: Wei Liao, Yanchen Liu, Lixiang Wang, Xiao Cai, Hong Xie, Faping Yi, Rongzhong Huang, Chui Fang, Peng Xie, Jian Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01267-0