Data-Driven Uncertainty Quantification for Cardiac Electrophysiological Models: Impact of Physiological Variability on Action Potential and Spiral Wave Dynamics

Data-Driven Uncertainty Quantification for Cardiac Electrophysiological Models: Impact of Physiological Variability on Action Potential and Spiral Wave Dynamics

Computational modeling of cardiac electrophysiology (EP) has recently transitioned from a scientific research tool to clinical applications. To ensure reliability of clinical or regulatory decisions made using cardiac EP models, it is vital to evaluate the uncertainty in model predictions. Model pre...

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Bibliographic Details
Main Authors: Pras Pathmanathan, Suran K. Galappaththige, Jonathan M. Cordeiro, Abouzar Kaboudian, Flavio H. Fenton, Richard A. Gray
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
uncertainty quantification
sensitivity analysis
variability
electrophysiology
correlation
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.585400/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.585400/full

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