Structure based drug discovery for designing leads for the non-toxic metabolic targets in multi drug resistant Mycobacterium tuberculosis

Structure based drug discovery for designing leads for the non-toxic metabolic targets in multi drug resistant Mycobacterium tuberculosis

Abstract Background The problem of drug resistance and bacterial persistence in tuberculosis is a cause of global alarm. Although, the UN’s Sustainable Development Goals for 2030 has targeted a Tb free world, the treatment gap exists and only a few new drug candidates are in the pipeline. In spite o...

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Bibliographic Details
Main Authors: Divneet Kaur, Shalu Mathew, Chinchu G. S. Nair, Azitha Begum, Ashwin K. Jainanarayan, Mukta Sharma, Samir K. Brahmachari
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Journal of Translational Medicine
Subjects:
Drug development
Drug resistance
Mycobacterium tuberculosis
Non-toxic targets
Structural biology
Systems biology
Online Access:http://link.springer.com/article/10.1186/s12967-017-1363-9

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http://link.springer.com/article/10.1186/s12967-017-1363-9

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