Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification

Abstract Background Published genetic risk scores for breast cancer (BC) so far have been based on a relatively small number of markers and are not necessarily using the full potential of large-scale Genome-Wide Association Studies. This study aimed to identify an efficient polygenic predictor for B...

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Bibliographic Details
Main Authors: Kristi Läll, Maarja Lepamets, Marili Palover, Tõnu Esko, Andres Metspalu, Neeme Tõnisson, Peeter Padrik, Reedik Mägi, Krista Fischer
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
Polygenic risk score
Genetic predisposition to disease
Breast cancer
Risk stratification
Personalized medicine
Online Access:http://link.springer.com/article/10.1186/s12885-019-5783-1

Internet

http://link.springer.com/article/10.1186/s12885-019-5783-1

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