ATN-224 enhances antitumor efficacy of oncolytic herpes virus against both local and metastatic head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequent cancer worldwide, and the 5-year survival rates are among the worst of the major cancers. Oncolytic herpes simplex viruses (oHSV) have the potential to make a significant impact in the targeted treatment of these patients. Here...

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Bibliographic Details
Main Authors: Ji Young Yoo, Jun-Ge Yu, Azeem Kaka, Quintin Pan, Pawan Kumar, Bhavna Kumar, Jianying Zhang, Andrew Mazar, Theodoros N Teknos, Balveen Kaur, Matthew O Old
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770516300109