Crystal Structure of a Ube2S-Ubiquitin Conjugate.

Protein ubiquitination occurs through the sequential formation and reorganization of specific protein-protein interfaces. Ubiquitin-conjugating (E2) enzymes, such as Ube2S, catalyze the formation of an isopeptide linkage between the C-terminus of a "donor" ubiquitin and a primary amino gro...

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Bibliographic Details
Main Authors: Sonja Lorenz, Moitrayee Bhattacharyya, Christian Feiler, Michael Rape, John Kuriyan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4734694?pdf=render