Fluorocyclisation via I(I)/I(III) catalysis: a concise route to fluorinated oxazolines

Fluorocyclisation via I(I)/I(III) catalysis: a concise route to fluorinated oxazolines

Herein, we describe a catalytic fluorooxygenation of readily accessible N-allylcarboxamides via an I(I)/I(III) manifold to generate 2-oxazolines containing a fluoromethyl group. Catalysis is conditional on the oxidation competence of Selectfluor®, whilst HF serves as both a fluoride source and Brøns...

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Bibliographic Details
Main Authors: Felix Scheidt, Christian Thiehoff, Gülay Yilmaz, Stephanie Meyer, Constantin G. Daniliuc, Gerald Kehr, Ryan Gilmour
Format: Article
Language:English
Published: Beilstein-Institut 2018-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
catalysis
cyclisation
fluorination
gauche effect
hypervalent iodine
oxazolines
Online Access:https://doi.org/10.3762/bjoc.14.88

Internet

https://doi.org/10.3762/bjoc.14.88

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