Identification of ligand binding sites of proteins using the Gaussian Network Model.

The nonlocal nature of the protein-ligand binding problem is investigated via the Gaussian Network Model with which the residues lying along interaction pathways in a protein and the residues at the binding site are predicted. The predictions of the binding site residues are verified by using severa...

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Bibliographic Details
Main Authors: Ceren Tuzmen, Burak Erman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3026835?pdf=render