Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity

Adjuvant-enhanced CD4 T Cell Responses are Critical to Durable Vaccine Immunity

Protein-based vaccines offer a safer alternative to live-attenuated or inactivated vaccines but have limited immunogenicity. The identification of adjuvants that augment immunogenicity, specifically in a manner that is durable and antigen-specific, is therefore critical for advanced development. In...

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Bibliographic Details
Main Authors: Karen A.O. Martins, Christopher L. Cooper, Sabrina M. Stronsky, Sarah L.W. Norris, Steven A. Kwilas, Jesse T. Steffens, Jacqueline G. Benko, Sean A. van Tongeren, Sina Bavari
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:EBioMedicine
Subjects:
Vaccine
Adjuvant
Durable protection
Immune correlates
Ebola virus
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415302243

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http://www.sciencedirect.com/science/article/pii/S2352396415302243

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