Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching

Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching

Fibrous extracellular matrix (ECM) proteins provide mechanical structure and adhesive scaffolding to resident cells within stromal tissues. Aligned ECM fibers play an important role in directing morphogenetic processes, supporting mechanical loads, and facilitating cell migration. Various methods ha...

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Bibliographic Details
Main Authors: Harrison L. Hiraki, Daniel L. Matera, Michael J. Rose, Robert N. Kent, Connor W. Todd, Mark E. Stout, Anya E. Wank, Maria C. Schiavone, Samuel J. DePalma, Alexander A. Zarouk, Brendon M. Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
electrospinning
fiber alignment
hydrogel
epithelial cell migration
tendon
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.679165/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.679165/full

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