NEPdb: A Database of T-Cell Experimentally-Validated Neoantigens and Pan-Cancer Predicted Neoepitopes for Cancer Immunotherapy

NEPdb: A Database of T-Cell Experimentally-Validated Neoantigens and Pan-Cancer Predicted Neoepitopes for Cancer Immunotherapy

T-cell recognition of somatic mutation-derived cancer neoepitopes can lead to tumor regression. Due to the difficulty to identify effective neoepitopes, constructing a database for sharing experimentally validated cancer neoantigens will be beneficial to precise cancer immunotherapy. Meanwhile, the...

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Bibliographic Details
Main Authors: Jiaqi Xia, Peng Bai, Weiliang Fan, Qiming Li, Yongzheng Li, Dehe Wang, Lei Yin, Yu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
neoantigen
HLA
cancer immunotherapy
somatic mutation
neoepitope
MHC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.644637/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.644637/full

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