Evolution of histone 2A for chromatin compaction in eukaryotes

During eukaryotic evolution, genome size has increased disproportionately to nuclear volume, necessitating greater degrees of chromatin compaction in higher eukaryotes, which have evolved several mechanisms for genome compaction. However, it is unknown whether histones themselves have evolved to reg...

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Bibliographic Details
Main Authors: Benjamin R Macadangdang, Amit Oberai, Tanya Spektor, Oscar A Campos, Fang Sheng, Michael F Carey, Maria Vogelauer, Siavash K Kurdistani
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/02792