Subunit vaccine consisting of multi-stage antigens has high protective efficacy against Mycobacterium tuberculosis infection in mice.

Subunit vaccine consisting of multi-stage antigens has high protective efficacy against Mycobacterium tuberculosis infection in mice.

To search for more effective tuberculosis (TB) subunit vaccines, antigens expressed in different growth stages of Mycobacterium tuberculosis (M. tuberculosis), such as RpfE (Rv2450c) produced in the stage of resuscitation, Mtb10.4 (Rv0288), Mtb8.4 (Rv1174c), ESAT6 (Rv3875), Ag85B (Rv1886c) mainly se...

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Bibliographic Details
Main Authors: Qi Xin, Hongxia Niu, Zhi Li, Guoping Zhang, Lina Hu, Bingxiang Wang, Jingjing Li, Hongjuan Yu, Wanbo Liu, Yue Wang, Zejiao Da, Ruiying Li, Qiaoyang Xian, Yong Wang, Ying Zhang, Tao Jing, Xingming Ma, Bingdong Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3744459?pdf=render

Internet

http://europepmc.org/articles/PMC3744459?pdf=render

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