FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

Biosynthesis of lipids was investigated in growing 293 cells stably expressing fatty acid (FA) transport protein 1 (FATP1), a bifunctional polypeptide with FA transport as well as fatty acyl-CoA synthetase activity. In short-term (30 s) incubations, FA uptake was increased in FATP1 expressing cells...

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Bibliographic Details
Main Authors: Grant M. Hatch, Anne J. Smith, Fred Y. Xu, Angela M. Hall, David A. Bernlohr
Format: Article
Language:English
Published: Elsevier 2002-09-01
Series:Journal of Lipid Research
Subjects:
transport
CoA synthetase
esterification
fatty acid transport protein 1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328017

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http://www.sciencedirect.com/science/article/pii/S0022227520328017

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