High Expression of DEPDC1 Promotes Malignant Phenotypes of Breast Cancer Cells and Predicts Poor Prognosis in Patients With Breast Cancer

High Expression of DEPDC1 Promotes Malignant Phenotypes of Breast Cancer Cells and Predicts Poor Prognosis in Patients With Breast Cancer

DEP domain containing 1 (DEPDC1) is a novel tumor-associated gene, which is aberrantly expressed in multiple types of cancer and involves in tumorigenesis and cancer progression. Here, we examined the functional involvement and underlying mechanism of DEPDC1 in breast cancer. In this study, the immu...

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Bibliographic Details
Main Authors: Huishan Zhao, Mingwei Yu, Laijian Sui, Benjiao Gong, Bo Zhou, Jian Chen, Zhaohua Gong, Cuifang Hao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
breast cancer
DEPDC1
TCGA
proliferation
PI3K/AKT/mTOR
GSEA
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00262/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00262/full

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