Autologous mesenchymal stromal cells embedded in tricalcium phosphate for posterolateral spinal fusion: results of a prospective phase I/II clinical trial with long-term follow-up

Autologous mesenchymal stromal cells embedded in tricalcium phosphate for posterolateral spinal fusion: results of a prospective phase I/II clinical trial with long-term follow-up

Abstract Background Posterolateral spinal fusion with autologous bone graft is considered the “gold standard” for lumbar degenerative disc disease (DDD) when surgical treatment is indicated. The potential role of mesenchymal stromal cells (MSCs) to replace the bone graft in this setting has not been...

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Bibliographic Details
Main Authors: Juan F. Blanco, Eva M. Villarón, David Pescador, Carmen da Casa, Victoria Gómez, Alba M. Redondo, Olga López-Villar, Miriam López-Parra, Sandra Muntión, Fermín Sánchez-Guijo
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Stem Cell Research & Therapy
Subjects:
Spine surgery
Autologous mesenchymal stromal cells
MSC
Spinal fusion
Lumbar degenerative disc disease
DDD
Online Access:http://link.springer.com/article/10.1186/s13287-019-1166-4

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http://link.springer.com/article/10.1186/s13287-019-1166-4

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