Exhausted T cells and epigenetic status

Exhausted T cells are a group of dysfunctional T cells, which are present in chronic infections or tumors. The most significant characteristics of exhausted T cells are attenuated effector cytotoxicity, reduced cytokine production, and upregulation of multiple inhibitory molecular receptors (e.g., P...

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Bibliographic Details
Main Authors: Ziqing Zeng, Feng Wei, Xiubao Ren
Format: Article
Language:English
Published: China Anti-Cancer Association 2020-11-01
Series:Cancer Biology & Medicine
Subjects:
tox
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1733