dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

Abstract Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing...

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Bibliographic Details
Main Authors: Viktor Petukhov, Jimin Guo, Ninib Baryawno, Nicolas Severe, David T. Scadden, Maria G. Samsonova, Peter V. Kharchenko
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-018-1449-6

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http://link.springer.com/article/10.1186/s13059-018-1449-6

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