dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Abstract Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-06-01
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Series: | Genome Biology |
Online Access: | http://link.springer.com/article/10.1186/s13059-018-1449-6 |