Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility.

To understand how Toll signaling controls the activation of a cellular immune response in Drosophila blood cells (hemocytes), we carried out a genetic modifier screen, looking for deletions that suppress or enhance the mobilization of sessile hemocytes by the gain-of-function mutation Toll10b (Tl10b...

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Bibliographic Details
Main Authors: Martin R Schmid, Ines Anderl, Hoa T M Vo, Susanna Valanne, Hairu Yang, Jesper Kronhamn, Mika Rämet, Tor Erik Rusten, Dan Hultmark
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4965076?pdf=render