Foxp4 is dispensable for T cell development, but required for robust recall responses.

Foxp4 is dispensable for T cell development, but required for robust recall responses.

Transcription factors regulate T cell fates at every stage of development and differentiation. Members of the Foxp family of forkhead transcription factors are essential for normal T lineage development; Foxp3 is required for T regulatory cell generation and function, and Foxp1 is necessary for gene...

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Bibliographic Details
Main Authors: Karla R Wiehagen, Evann Corbo-Rodgers, Shanru Li, Elizabeth S Staub, Christopher A Hunter, Edward E Morrisey, Jonathan S Maltzman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3418275?pdf=render

Internet

http://europepmc.org/articles/PMC3418275?pdf=render

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