Persistent HIV-1 transcription in CD4+ T cells from ART-suppressed individuals can originate from biologically competent proviruses

HIV-1 is able to persist in the face of potent antiretroviral therapy (ART). A number of strategies are being explored to allow ART-free viral remission or viral eradication. In order to gauge the progress of these strategies, assays with which to measure viral reservoir size and activity are needed...

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Bibliographic Details
Main Authors: M. Vignoles, V. Andrade, M. Noguera, C. Brander, C. Mavian, M. Salemi, R. Paredes, M. Sharkey, M. Stevenson
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Virus Eradication
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664021000261