CtIP is required to initiate replication-dependent interstrand crosslink repair.

CtIP is required to initiate replication-dependent interstrand crosslink repair.

DNA interstrand crosslinks (ICLs) are toxic lesions that block the progression of replication and transcription. CtIP is a conserved DNA repair protein that facilitates DNA end resection in the double-strand break (DSB) repair pathway. Here we show that CtIP plays a critical role during initiation o...

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Bibliographic Details
Main Authors: Michelle L Duquette, Qingyuan Zhu, Ewan R Taylor, Angela J Tsay, Linda Z Shi, Michael W Berns, Clare H McGowan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23144634/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23144634/?tool=EBI

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