Promoter Methylation Status Modulate the Expression of Tumor Suppressor (RbL2/p130) Gene in Breast Cancer.

Promoter Methylation Status Modulate the Expression of Tumor Suppressor (RbL2/p130) Gene in Breast Cancer.

Aberrant expression of tumor suppressor genes may correspond to the abnormal cell development and tumorigenesis. Rbl2/p130, a member of retinoblastoma family of proteins, has growth suppressive properties. Numerous studies reported de-regulation of Rbl2/p130 in various types of cancer as a consequen...

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Bibliographic Details
Main Authors: Farman Ullah, Taimoor Khan, Nawab Ali, Faraz Arshad Malik, Mahmood Akhtar Kayani, Syed Tahir Abbas Shah, Muhammad Saeed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4536218?pdf=render

Internet

http://europepmc.org/articles/PMC4536218?pdf=render

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