Mirtazapine inhibits tumor growth via immune response and serotonergic system.

To study the tumor inhibition effect of mirtazapine, a drug for patients with depression, CT26/luc colon carcinoma-bearing animal model was used. BALB/c mice were randomly divided into six groups: two groups without tumors, i.e. wild-type (no drug) and drug (mirtazapine), and four groups with tumors...

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Main Authors: Chun-Kai Fang, Hong-Wen Chen, I-Tsang Chiang, Chia-Chieh Chen, Jyh-Fei Liao, Ton-Ping Su, Chieh-Yin Tung, Yosuke Uchitomi, Jeng-Jong Hwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3396612?pdf=render