Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

Summary: Circular RNAs constitute a unique class of RNAs whose precise functions remain to be elucidated. In particular, cancer-associated chromosomal translocations can give rise to fusion circular RNAs that play a role in leukemia progression. However, how and when fusion circular RNAs are formed...

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Bibliographic Details
Main Authors: Loelia Babin, Marion Piganeau, Benjamin Renouf, Khadija Lamribet, Cecile Thirant, Ludovic Deriano, Thomas Mercher, Carine Giovannangeli, Erika C. Brunet
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900421830083X