Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity.

Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity.

There is recent evidence that galectin-3 participates in immunity to infections, mostly by tuning cytokine production. We studied the balance of Th1/Th2 responses to P. brasiliensis experimental infection in the absence of galectin-3. The intermediate resistance to the fungal infection presented by...

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Bibliographic Details
Main Authors: Luciana Pereira Ruas, Emerson Soares Bernardes, Marise Lopes Fermino, Leandro Licursi de Oliveira, Daniel K Hsu, Fu-Tong Liu, Roger Chammas, Maria-Cristina Roque-Barreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2641003?pdf=render

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http://europepmc.org/articles/PMC2641003?pdf=render

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