Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4+ T cells and ameliorates rheumatoid arthritis

Supranutritional selenium suppresses ROS‐induced generation of RANKL‐expressing osteoclastogenic CD4+ T cells and ameliorates rheumatoid arthritis

Abstract Objective The benefit of Se supplementation in rheumatoid arthritis (RA) has been tested in clinical trials, but results remain inconclusive. The objective of this study was to specifically investigate the potential benefit of supranutritional Se by examining human samples from an area with...

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Bibliographic Details
Main Authors: Jiahuan Qin, Xia Huang, Naiqi Wang, Pengcheng Zhou, Hao Zhang, Zhian Chen, Kaili Liang, Dongcheng Gong, Qunxiong Zeng, Peng Niu, Anping Chen, Lin Yuan, Zhaohui Yang, Linchong Su, Nan Shen, Jun Deng, Di Yu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
RANKL
rheumatoid arthritis
selenium
Th17 cells
Online Access:https://doi.org/10.1002/cti2.1338

Internet

https://doi.org/10.1002/cti2.1338

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