Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of <i>Lycopodii Herba</i> Extract by LC-MS/MS

Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of <i>Lycopodii Herba</i> Extract by LC-MS/MS

<i>Lycopodii Herba</i> is a widely used traditional medicinal herb, and contains diverse fascinating alkaloids. In this study, a fast and sensitive LC-MS/MS method for the simultaneous determination of lycodoline, &#945;-obscurine, and <i>N</i>-demethyl-&#945;-obscuri...

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Bibliographic Details
Main Authors: Dongke Ma, Xiaoting Gu, Xin Wang, Youping Liu, Xin Di
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
<i>Lycopodii Herba</i>
lycodoline
α-obscurine
<i>N</i>-demethyl-α-obscurine
pharmacokinetics
brain tissue distribution
liquid chromatography–tandem mass spectrometry
Online Access:https://www.mdpi.com/1420-3049/24/10/1930

Internet

https://www.mdpi.com/1420-3049/24/10/1930

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