DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins

Several studies have linked DNA methylation at individual CpG sites to aging and various diseases. Recent studies have also identified single CpGs whose methylation levels are associated with all-cause mortality. In this study, we perform an epigenome-wide study of the association between CpG methyl...

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Bibliographic Details
Main Authors: Anne Marie Svane, Mette Soerensen, Jesper Lund, Qihua Tan, Juulia Jylhävä, Yunzhang Wang, Nancy L. Pedersen, Sara Hägg, Birgit Debrabant, Ian J. Deary, Kaare Christensen, Lene Christiansen, Jacob B. Hjelmborg
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Genes
Subjects:
DNA methylation
mortality
EWAS
survival analysis
survival prediction
twin study
heritability
Online Access:http://www.mdpi.com/2073-4425/9/2/78

Internet

http://www.mdpi.com/2073-4425/9/2/78

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