Identification of a role for the PI3K/AKT/mTOR signaling pathway in innate immune cells.

The innate immune system is the first line of host defense against infection and involves several different cell types. Here we investigated the role of the phosphatidylinositol 3 kinase (PI3K) signaling pathway in innate immune cells. By blocking this pathway with pharmacological inhibitors, we fou...

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Bibliographic Details
Main Authors: Songbo Xie, Miao Chen, Bing Yan, Xianfei He, Xiwen Chen, Dengwen Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3981814?pdf=render