Subversion of cellular autophagosomal machinery by RNA viruses.

Infection of human cells with poliovirus induces the proliferation of double-membraned cytoplasmic vesicles whose surfaces are used as the sites of viral RNA replication and whose origin is unknown. Here, we show that several hallmarks of cellular autophagosomes can be identified in poliovirus-induc...

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Bibliographic Details
Main Authors: William T Jackson, Thomas H Giddings, Matthew P Taylor, Sara Mulinyawe, Marlene Rabinovitch, Ron R Kopito, Karla Kirkegaard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0030156