The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans

The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans

Cataplexy, an emotion-triggered sudden loss of muscle tone specific to narcolepsy, is tightly associated with hypocretin deficiency. Using hypocretin receptor 2 gene (hcrtr 2)-mutated narcoleptic Dobermans, we have previously demonstrated that altered dopamine (DA) D2/3 receptor mechanisms in mesenc...

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Bibliographic Details
Main Authors: Mutsumi Okura, Nobuhiro Fujiki, Ichiro Kita, Kazuki Honda, Yasushi Yoshida, Emmanuel Mignot, Seiji Nishino
Format: Article
Language:English
Published: Elsevier 2004-06-01
Series:Neurobiology of Disease
Subjects:
Cataplexy
Narcolepsy
Dopamine
Autoreceptor
A11
Diencephalic dopaminergic system
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104000427

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http://www.sciencedirect.com/science/article/pii/S0969996104000427

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