Converting redox signaling to apoptotic activities by stress-responsive regulators HSF1 and NRF2 in fenretinide treated cancer cells.

<h4>Background</h4>Pharmacological intervention of redox balance in cancer cells often results in oxidative stress-mediated apoptosis, attracting much attention for the development of a new generation of targeted therapy in cancer. However, little is known about mechanisms underlying the...

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Bibliographic Details
Main Authors: Kankan Wang, Hai Fang, Dakai Xiao, Xuehua Zhu, Miaomiao He, Xiaoling Pan, Jiantao Shi, Hui Zhang, Xiaohong Jia, Yanzhi Du, Ji Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19844581/?tool=EBI