Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Deconstructing sarcomeric structure–function relations in titin-BioID knock-in mice

Titin determines the elasticity of the sarcomere and integrates into both the Z-disc and the M-band. Here, the authors generate a BioID mouse to study the titin interactome at the Z-disc region in neonatal and adult heart and skeletal muscle.

Bibliographic Details
Main Authors: Franziska Rudolph, Claudia Fink, Judith Hüttemeister, Marieluise Kirchner, Michael H. Radke, Jacobo Lopez Carballo, Eva Wagner, Tobias Kohl, Stephan E. Lehnart, Philipp Mertins, Michael Gotthardt
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16929-8

Internet

https://doi.org/10.1038/s41467-020-16929-8

Similar Items