Extracellular Vesicles Released by Leishmania (Leishmania) amazonensis Promote Disease Progression and Induce the Production of Different Cytokines in Macrophages and B-1 Cells

The extracellular vesicles (EVs) released by Leishmania can contribute to the establishment of infection and host immunomodulation. In this study, we characterized the shedding of EVs from Leishmania (Leishmania) amazonensis promastigotes. This species is the causative agent of cutaneous leishmanias...

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Main Authors: Fernanda Marins Costa Barbosa, Talita Vieira Dupin, Mayte dos Santos Toledo, Natasha Ferraz dos Campos Reis, Kleber Ribeiro, André Cronemberger-Andrade, Jeronimo Nunes Rugani, Beatriz Helena Pizarro De Lorenzo, Ronni Rômulo Novaes e Brito, Rodrigo Pedro Soares, Ana Claudia Torrecilhas, Patricia Xander
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03056/full