Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5

Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5

Abstract Background Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between neoplasms can be unique, allowing for distinctions in malignancy, invasion and chemoresistance between cancer types and subt...

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Bibliographic Details
Main Authors: Julie A. MacDonald, Niharika Kura, Carleigh Sussman, Dori C. Woods
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Ovarian Research
Subjects:
Granulosa cell tumor
KGN
Mitochondria
Metabolism
TRAIL
BIRC5
Online Access:http://link.springer.com/article/10.1186/s13048-018-0463-3

Internet

http://link.springer.com/article/10.1186/s13048-018-0463-3

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