A Chemical Screening Approach to Identify Novel Key Mediators of Erythroid Enucleation.

A Chemical Screening Approach to Identify Novel Key Mediators of Erythroid Enucleation.

Erythroid enucleation is critical for terminal differentiation of red blood cells, and involves extrusion of the nucleus by orthochromatic erythroblasts to produce reticulocytes. Due to the difficulty of synchronizing erythroblasts, the molecular mechanisms underlying the enucleation process remain...

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Bibliographic Details
Main Authors: Christina B Wölwer, Luke B Pase, Helen B Pearson, Nathan J Gödde, Kurt Lackovic, David C S Huang, Sarah M Russell, Patrick O Humbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4646491?pdf=render

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http://europepmc.org/articles/PMC4646491?pdf=render

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