Variation in the Cox-2 Gene May Modify the Effect of Alendronate on Vertebral Fracture Prevention
Bisphosphonates such as alendronate, which are potent specific inhibitors of osteoclast-mediated bone resorption, are widely used for treatment of postmenopausal osteoporosis as well as other diseases related to bone remodeling. We evaluated whether the reportedly functional PTGS2 (prostaglandin-end...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-09-01
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Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/1721727X1000800302 |