Variation in the Cox-2 Gene May Modify the Effect of Alendronate on Vertebral Fracture Prevention

Bisphosphonates such as alendronate, which are potent specific inhibitors of osteoclast-mediated bone resorption, are widely used for treatment of postmenopausal osteoporosis as well as other diseases related to bone remodeling. We evaluated whether the reportedly functional PTGS2 (prostaglandin-end...

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Bibliographic Details
Main Authors: A. Hossein-Nezhad, K. Mirzaei, F. Birami Jamal, R. Mirfakhraei, N. Sedighi
Format: Article
Language:English
Published: SAGE Publishing 2010-09-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1000800302