Effects of Curcumin against Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor Metalloproteinase-2 (TIMP-2) Serum Level on Rat Model of Liver Fibrosis Resolution Process

Effects of Curcumin against Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor Metalloproteinase-2 (TIMP-2) Serum Level on Rat Model of Liver Fibrosis Resolution Process

Background: Liver fibrosis is an effect from continuous fibrogenesis and fibrolysis process. During fibrogenesis, MMP-2 and TIMP-2 that produced by hepatic stellate cell (HSC) have a role to regulate extracellular matrix (ECM) homeostastic. Otherwise, curcumin inhibits both MMP-2 and TIMP-2 expressi...

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Bibliographic Details
Main Authors: Supriono, Bogi Pratomo, Muhammad Kriestian
Format: Article
Language:English
Published: Interna Publishing 2018-04-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Subjects:
rat model of liver fibrosis
carbon tetrachloride
curcumin
MMP-2
TIMP-2
Online Access:http://ina-jghe.com/journal/index.php/jghe/article/view/653/522

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http://ina-jghe.com/journal/index.php/jghe/article/view/653/522

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