Concerted Action of ANP and Dopamine D1-Receptor to Regulate Sodium Homeostasis in Nephrotic Syndrome

The edema formation in nephrotic syndrome (NS) is associated with a blunted response to atrial natriuretic peptide (ANP). The natriuretic effects of ANP have been related to renal dopamine D1-receptors (D1R). We examined the interaction between ANP and renal D1R in rats with puromycin aminonucleosid...

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Main Authors: Cátia Fernandes-Cerqueira, Benedita Sampaio-Maia, Janete Quelhas-Santos, Mónica Moreira-Rodrigues, Liliana Simões-Silva, Ana M. Blazquez-Medela, C. Martinez-Salgado, Jose M. Lopez-Novoa, Manuel Pestana
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/397391