Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes

Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes

A copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and terminal alkynes is reported. The alkyl carboxylic acids is for the first time being used as the alkyl azide precursors in the...

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Bibliographic Details
Main Authors: Muhammad Israr, Changqing Ye, Munira Taj Muhammad, Yajun Li, Hongli Bao
Format: Article
Language:English
Published: Beilstein-Institut 2018-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
alkyl diacyl peroxides
azidotrimethylsilane
click reaction
copper catalysis
radical
1,2,3-triazoles
Online Access:https://doi.org/10.3762/bjoc.14.270

Internet

https://doi.org/10.3762/bjoc.14.270

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