Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii.

Toxoplasma gondii is an obligate intracellular parasite that can infect virtually all nucleated cells in warm-blooded animals. The ability of Toxoplasma tachyzoites to infect and successfully manipulate its host is dependent on its ability to transport "GRA" proteins that originate in uniq...

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Bibliographic Details
Main Authors: Nicole D Marino, Michael W Panas, Magdalena Franco, Terence C Theisen, Adit Naor, Suchita Rastogi, Kerry R Buchholz, Hernan A Lorenzi, John C Boothroyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5794187?pdf=render