Dexmedetomidine-Induced Contraction Involves CPI-17 Phosphorylation in Isolated Rat Aortas

Dexmedetomidine, a highly selective α-2 adrenoceptor agonist, produces vasoconstriction, which leads to transiently increased blood pressure. The goal of this study was to investigate specific protein kinases and the associated cellular signal pathways responsible for the increased calcium sensitiza...

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Bibliographic Details
Main Authors: Seong-Ho Ok, Seong-Chun Kwon, Jiseok Baik, Jeong-Min Hong, Jiah Oh, Jeong Yeol Han, Ju-Tae Sohn
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/17/10/1663