MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms.

MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms.

The monocyte chemotactic protein-1 (MCP-1) is a chemokine that plays an important role in the recruitment of monocytes to M. tuberculosis infection sites, and previous studies have reported that genetic variants in MCP1 are associated with differential susceptibility to pulmonary tuberculosis (PTB)....

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Bibliographic Details
Main Authors: Digna R Velez Edwards, Alessandra Tacconelli, Christian Wejse, Philip C Hill, Gerard A J Morris, Todd L Edwards, John R Gilbert, Jamie L Myers, Yo Son Park, Martin E Stryjewski, Eduardo Abbate, Rosa Estevan, Paulo Rabna, Giuseppe Novelli, Carol D Hamilton, Richard Adegbola, Lars Østergaar, Scott M Williams, William K Scott, Giorgio Sirugo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3288089?pdf=render

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http://europepmc.org/articles/PMC3288089?pdf=render

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