“Liquid Biopsy” of White Matter Hyperintensity in Functionally Normal Elders

“Liquid Biopsy” of White Matter Hyperintensity in Functionally Normal Elders

Background and Objective: In the aging brain, increased blood-brain barrier (BBB) leakage and white matter hyperintensity (WMH) on MRI are frequently presumed secondary to cerebral small vessel disease (cSVD) or endotheliopathy. We investigate this association in vivo by quantifying protein cargo fr...

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Bibliographic Details
Main Authors: Fanny M. Elahi, Kaitlin B. Casaletto, Marie Altendahl, Adam M. Staffaroni, Evan Fletcher, Teresa J. Filshtein, Maria M. Glymour, Bruce L. Miller, Jason D. Hinman, Charles DeCarli, Edward J. Goetzl, Joel H. Kramer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
cerebral small vessel disease
exosomes
extracellular vesicles
biomarkers
white matter
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00343/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00343/full

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