Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy

Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy

Myocardial infarction is the leading cause of morbidity and mortality worldwide. Although myocardial reperfusion after ischemia (I/R) is an effective method to save ischemic myocardium, it can cause adverse reactions, including increased oxidative stress and cardiomyocyte apoptosis. Mitochondrial fi...

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Bibliographic Details
Main Authors: Tzu-Lin Lee, Ming-Hsueh Lee, Yu-Chen Chen, Yi-Chieh Lee, Tsai-Chun Lai, Hugo You-Hsien Lin, Lee-Fen Hsu, Hsin-Ching Sung, Chiang-Wen Lee, Yuh-Lien Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
cardiac ischemia/reperfusion
mitochondrial fission
vitamin D3
apoptosis
mitophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.604700/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.604700/full

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