Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress

<p>Abstract</p> <p>Background</p> <p>Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepa...

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Bibliographic Details
Main Authors: Yang Chaofeng, Wang Cong, Ye Min, Jin Chengliu, He Weimin, Wang Fen, McKeehan Wallace L, Luo Yongde
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Nutrition & Metabolism
Subjects:
FGF
Online Access:http://www.nutritionandmetabolism.com/content/9/1/94