The stretcher spontaneous neurodegenerative mutation models Charcot-Marie-Tooth disease type 4D [v1; ref status: indexed, http://f1000r.es/8c]

The stretcher spontaneous neurodegenerative mutation models Charcot-Marie-Tooth disease type 4D [v1; ref status: indexed, http://f1000r.es/8c]

Mice affected by a spontaneous mutation which arose within our colony exhibited a neuromuscular phenotype involving tremor and characteristic stretching of the rear limbs. The mutant, named stretcher, was used to breed a backcross cohort for genetic mapping studies. The gene responsible for the muta...

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Bibliographic Details
Main Authors: David Chandler, Sash Lopaticki, Dexing Huang, Michael Hunter, Dora Angelicheva, Trevor Kilpatrick, Rosalind HM King, Luba Kalaydjieva, Grant Morahan
Format: Article
Language:English
Published: F1000 Research Ltd 2013-02-01
Series:F1000Research
Subjects:
Neurobiology of Disease & Regeneration
Neurogenetics
Peripheral Neuropathies
Online Access:http://f1000research.com/articles/2-46/v1

Internet

http://f1000research.com/articles/2-46/v1

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