G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

Summary: Dysregulated gene expression is a common feature of cancer and may underlie some aspects of tumor progression, including tumor relapse. Here, we show that recurrent mammary tumors exhibit global changes in gene expression and histone modifications and acquire dependence on the G9a histone m...

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Bibliographic Details
Main Authors: Nathaniel W. Mabe, Nina Marie G. Garcia, Shayna E. Wolery, Rachel Newcomb, Ryan C. Meingasner, Brittany A. Vilona, Ryan Lupo, Chao-Chieh Lin, Jen-Tsan Chi, James V. Alvarez
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Cell Reports
Subjects:
G9a
breast cancer
recurrence
epigenetics
necroptosis
RIPK3
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720313309

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http://www.sciencedirect.com/science/article/pii/S2211124720313309

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