EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial

EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial

Abstract Background Despite advances in immunosuppressive therapy, kidney graft survival has failed to improve during the last decades. Ischemia/reperfusion injury (IRI) is one of the main pathophysiological mechanisms underlying delayed graft function, which is associated with poor long-term graft...

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Bibliographic Details
Main Authors: Sophie Girerd, Luc Frimat, Didier Ducloux, Yannick Le Meur, Christophe Mariat, Bruno Moulin, Christiane Mousson, Philippe Rieu, Nassim Dali-Youcef, Ludovic Merckle, Xavier Lepage, Patrick Rossignol, Nicolas Girerd, Frédéric Jaisser
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Trials
Subjects:
Mineralocorticoid receptor antagonist
Ischemia/reperfusion lesions
Kidney transplantation
Expanded criteria donor
Randomized controlled trial
Online Access:http://link.springer.com/article/10.1186/s13063-018-2956-1

Internet

http://link.springer.com/article/10.1186/s13063-018-2956-1

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